Discovering Brain and Muscle Treatment Targets for Post-Traumatic Headache
Katrina Maluf


Exercise and Nutritional Sciences
Dr. Maluf (left) and research assistant Mike Walsh (right) discuss functional magnetic resonance imaging (fMRI) of the brain and neck.
Nearly 1.7 million individuals sustain a traumatic brain injury (TBI) requiring medical attention every year in the U.S. Nearly half of those who sustain a TBI report residual disability from post-concussive symptoms that can persist for years after injury. Post-traumatic headache (PTH) is the most common and debilitating of these symptoms.
Dr. Katrina Maluf and colleagues at UCSD and the Veteran’s Administration San Diego Healthcare System are using advanced quantitative sensory testing and magnetic resonance imaging techniques to identify brain and muscle biomarkers of PTH and chronic neck pain in veterans with mild TBI. This work will improve the diagnosis and treatment of PTH to reduce the burden of chronic pain in military service members, veterans, athletes, and others impacted by TBI.

This research is supported by the National Institute of Neurological Disorders and Stroke (1R21NS109852-01A1).

